Abstract CRISPR-associated (Cas) transposases (CAST) are RNA-guided systems capable of programmable integration of large segments of DNA without creating double-strand breaks.Engineered Cascade CAST function in human cells but are Drying Racks challenging to deploy due to the complexity of the targeting components.Unlike Cascade, which require thre
Prevention of alcohol related harm though preconception care: A scoping review of barriers and enablers
Objective: To understand the perspectives of healthcare practitioners and women of reproductive age regarding addressing prevention of an alcohol exposed pregnancy before conception.Methods: A scoping review of mixed methods, qualitative and quantitative research was conducted.Medline, CINAHL, 9PV EMBASE and PsychInfo databases were searched for li
Simultaneous Determination of Metamizole, Thiamin and Pyridoxin Using UV-Spectroscopy in Combination with Multivariate Calibration
Purpose: Analysis of drugs in multicomponent system officially is carried out using chromatographic technique, however, this technique is too laborious and involving sophisticated instrument.Therefore, UV-VIS spectrophotometry coupled with multivariate calibration of partial least square (PLS) for quantitative analysis of metamizole, thiamin and py
Transition to Smart and Regenerative Urban Places (SRUP): Contributions to a New Conceptual Framework
Modern urbanism is called to face current challenges ranging from intensive demographic growth, economic and social stagnation to resources salvation and climate changes.Under the broader scope of sustainability, we argue that the transition to a Wigs holistic perspective of smart and regenerative planning and design is the way to face and yet to p
Familial Mediterranean Fever (FMF): Mysterious Presentations and Challenging Points From Diagnosis to Management in Acute Care Settings; A Literature Review
Introduction: Familial Mediterranean fever (FMF) is an autosomal recessive disease considered to be the most common entity of a rare group of disorders known as auto-inflammatory syndromes which have acute presentations in emergency settings.Methods: A search of Web of Science, Google Scholar, Cochrane, and PubMed databases for articles published b